A warning icon appears next to each feature in the list when navigating to the Exim Configuration Manager.
When logging into the WHM and you navigate to the Exim Configuration Manager, an icon with a warning appears alerting you the options have not been saved yet.
This is found in Home » Service Configuration » Exim Configuration Manager
Note that a warning icon before an option indicates that it has not been previously set.
Please review all new options carefully before saving your changes.
Options in italics are unavailable because of other options that are set
Simply save the page and this will populate the option to the /etc/exim.conf.localopts file.