Introduction
LiteSpeed automatically populates its configuration based on the server's Apache settings; LiteSpeed also has additional settings in its admin panel that can be set to optimize your site.
Answer:
If you use WordPress, the easiest way to increase the performance of your website is to enable the WordPress caching plugin.
How to enable LiteSpeed cache for WordPress installations via the LiteSpeed plugin for WHM
For more advanced tuning, LiteSpeed has two guides, one for shared hosting and one for a server dedicated to a single site: